1. Management of Acetaminophen Poisoning in the US and Canada: A Consensus Statement
Intentional overdoses are on the rise, with acetaminophen (Tylenol) remaining a common agent due to its widespread availability. This article reviews current best practices in managing acetaminophen toxicity, clearly defining acute ingestion as occurring within a 24-hour period. It also addresses the management of repeated supratherapeutic dosing, extended-release formulations, co-ingestions, and special populations including patients over 100 kg, children under 6 years old, and pregnant individuals. With significant variability in treatment approaches across institutions, this piece offers practical guidance to help standardize your management. Be sure to screenshot the included charts—they’re concise, easy to reference, and perfect for quick decision-making in the ED.
2. Toxic Tetrahydrocannabinol (THC) Dose in Pediatric Cannabis Edible Ingestions
With the growing legalization and availability of THC products, pediatric ED visits related to edible ingestion are on the rise. It’s important to remember that in children under 6 years of age, as little as 1.7 mg/kg of THC can result in severe and prolonged toxicity.
3. Naloxone Dispensing to Youth Ages 10–19: 2017–2022
Naloxone (Narcan) should be more routinely prescribed in high-risk households and whenever opioids are prescribed. As pediatric emergency medicine providers, we play a critical role in preventing both intentional and unintentional opioid overdoses. This article explores actionable ways we can increase access to Narcan and expand its availability within the community.

Rosemary Beggins, CRNP, is a Pediatric Nurse Practitioner in the Emergency Department at the Children’s Hospital of Philadelphia. She can be reached at BEGGINSRC@chop.edu.


